Hayden Petterson

  • Hayden Petterson posted an update 2 months ago

    Improved Cell Cycle Compound Library of generalized weighting factor functionsPieces of work made by V. Cech form the core of the theory [33,34].ConclusionThis article presents our newly-conceived theory of generalized meteo-ballistic weighting factor functions – WFF as a special kind of sensitivity functions – Fig. 10. The limited extent of this…[Read more]

  • Hayden Petterson posted an update 2 months ago

    IntroductionIntegrating smart technologies into existing houses generally requires major renovations, which may be as time consuming and/or costly as building a new house. Given that uric acid a building may last for decades, the requirements to allow incremental integrations of smart technologies into buildings outweigh those of new smart…[Read more]

  • Hayden Petterson posted an update 2 months ago

    Despite well known developmental differences in tissue regeneration and scar formation, very little is known about the differences in phenotype and regenerative capacity of stem cells isolated from different human developmental stages. Although there is evidence that allogeneic stem cells promote bone repair, many tissue-engineering studies have…[Read more]

  • Hayden Petterson posted an update 2 months ago

    Sources of Funding/Conflicts of InterestThis study was funded by grants from the R.J. Fasenmeyer Center for Clinical Immunology at the Cleveland Clinic, Case Western Reserve University Rottman Fund, ASTMH Benjamin H. Kean Fellowship, IDSA Medical Scholars Program, the NIH-NIAIDR01 AI090118, R01 A1068063, the American College of Rheumatology…[Read more]

  • Hayden Petterson posted an update 2 months ago

    To investigate the translatability of CR’s beneficial effects from rodents to primates, three independent rhesus monkey studies were initiated in the late 1980’s. Two of these studies are ongoing: one at the National Institute on Aging (NIA) and the other at the Wisconsin National Primate Research Center based at the University of Wisconsin…[Read more]

  • IntroductionType 2 diabetes (T2D) affects 380 million individuals worldwide, and its prevalence will further increase in the coming decades with the obesity epidemic (IDF Diabetes Atlas, 2013). T2D is characterized by progressive loss of pancreatic β cell function and insulinopenia, and by non-suppressed post-prandial glucagon secretion by…[Read more]

  • IntroductionFor a healthy and productive life, good sleep is essential, which has prompted studies on how comfortable sleep can be achieved (Ishiguro et al., 2006). For comfortable sleep, it is very important to create an indoor thermal environment, which could still be improved. Understanding the relationship between thermal environment,…[Read more]

  • To further determine the generality of our finding that iPSCs harbor unique transversion-predominant point mutation profiles (Figure S2D, left), we analyzed previously reported point mutation profiles in 27 different iPSC lines that had been established by various methods, including retrovirus, plasmid, and mRNA methods (Gore et al., 2011; Ji e…[Read more]

  • ResultsDiscussionhESCs demonstrate the potential to serve as a starting cell population for bone regeneration, and previous studies report effective differentiation of hESCs to osteogenic lineage (Arpornmaeklong et al., 2010; Kärner et al., 2009). However, it remains important to better define how to obtain homogeneous osteogenic progenitor GS-7340…[Read more]

  • While the current discussion largely restricts itself to neuroimaging methods that can make spatial inferences, ERP studies of RS have found similar results: while there is evidence of auditory RS involving both temporal and frontal cortices (Dehaene-Lambertz and Dehaene, 1994), ERP studies of visual RS have also largely reported a lack of visual…[Read more]

  • CRISPR Cas9 Tips and TricksDario Lupianez and Malte Spielmann (Berlin, Germany) held an engaging workshop titled CRISPR Cas9 tips and tricks. The aim was to demonstrate how this genome editing technology can be utilized in embryonic stem reverse transcriptase (ESCs) to produce genomic structural variations (SVs) in mice within ten weeks. This…[Read more]

  • For HCC, the second leading cause of cancer death worldwide, there is a lack of effective drugs. The only approved drug, sorafenib, has modest survival benefits (Llovet et al., 2008; Abou-Alfa et al., 2006; Cheng et al., 2009). Immunotherapy has been considered as an effective approach for cancer treatment, but the clinical benefits vary due to…[Read more]

  • The addition of hard phase reinforcement particles make MMCs brittle [18]. In many engineering applications, the service life of materials mainly depends on the surface properties of materials. Therefore, SCs are mostly prepared by combining a ductile metallic matrix with hard ceramic reinforcement up to a desired depth. The soundness of SCs apart…[Read more]

  • Since the normal mechanism of functioning of the system has not yet been discovered, any new theoretical framework of a mechanism is expected to provide an explanation for the functional role of sleep [18]. Difficulties in understanding the mechanisms of higher Caspase-5, human recombinant protein functions still continue, primarily because…[Read more]

  • Cuando la cantidad de euros fabricados por el bce aumentó, estos fueron parcialmente cambiados contra otras divisas, lo que provocó que el tipo de cambio del euro bajara. Para algunos países como España, esta baja alentó las exportaciones. Pero basta con observar el mercado de trabajo español devastado, donde los salarios son muy bajos, para darse…[Read more]

  • CorrelationHardness and ultrasonic wave velocity measurements are performed before and after each annealing stage. Their variation in initial condition are investigated in terms of annealing temperature, and then the variations of hardness and ultrasonic wave velocity are correlated for each steel type. The initial hardnesses of steel samples are…[Read more]

  • Timing of surgery after neoadjuvant chemoradiation therapyThe optimal timing of interval surgery remains unclear. When a surgeon chooses either short- or long-course RT, surgery should be undertaken within 2 weeks or after 6 weeks, respectively, to avoid severe tissue edema and postoperative morbidity. However, to gain the benefit of tumor…[Read more]

  • The induced expression of hADC was confirmed by immunostaining and western blotting (Fig. 1A&B). The over-expression of hADC genes significantly increased endogenous agmatine (Fig. 1C). Adherence of ginsenoside rh2 is important for differentiation as well as for proliferation, migration, neurite outgrowth, and synaptogenesis [65]. The cell…[Read more]

  • La participación del salario en la economía de acuerdo hordenine dissolve solubility cuentas nacionales es de 28%. Por lo que la participación del trabajo en los costos totales es de 48%Primero obtenemos el efecto en precios para cada escenario. En un mercado de bienes competitivo, y si los incrementos en salarios se pasan completamente al co…[Read more]

  • ICl with aberrant features are not observed in and mice. Rather, comparison of the reduction in [peak ICl]max and gClmax observed in and mice with the semi-quantitative immunohistochemical analysis of Clc-1 in these animals support the hypothesis that the decrease in ICl in these two strains may be at least in part a consequence of the…[Read more]

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