Davis Blalock

  • Other mitochondrion-related cellular alterations that are important in modulating apoptotic include induction of ROS. We observed that CSC vapor-selected acquisition of resistance to cisplatin was marked by the presence of decreased mitochondrial membrane potential and increased basal levels of ROS. Comparable levels of ROS generation and DYm…[Read more]

  • Our data suggest that Plin2 deficiency prevents these alcohol mediated effects on glucose tolerance. Our future studies will investigate specific mechanisms by which Plin2 deficiency protects against pancreatic beta cell dysfunction and glucose intolerance. Bioactive lipid metabolites can impair insulin signaling. In ALD, ceramides accumulate in…[Read more]

  • Our data suggest that Plin2 deficiency prevents these alcohol mediated effects on glucose tolerance. Our future studies will investigate specific mechanisms by which Plin2 deficiency protects against pancreatic beta cell dysfunction and glucose intolerance. Bioactive lipid metabolites can impair insulin signaling. In ALD, ceramides accumulate in…[Read more]

  • Other mitochondrion-related cellular alterations that are important in modulating apoptotic include induction of ROS. We observed that CSC vapor-selected acquisition of resistance to cisplatin was marked by the presence of decreased mitochondrial membrane potential and increased basal levels of ROS. Comparable levels of ROS generation and DYm…[Read more]

  • Our data suggest that Plin2 deficiency prevents these alcohol mediated effects on glucose tolerance. Our future studies will investigate specific mechanisms by which Plin2 deficiency protects against pancreatic beta cell dysfunction and glucose intolerance. Bioactive lipid metabolites can impair insulin signaling. In ALD, ceramides accumulate in…[Read more]

  • Davis Blalock posted an update 1 week, 1 day ago

    Besides breast cancer, aberrant expression of SATB1 was also correlated with advanced clinicopathologic factors and poor prognosis in cases of glioma, melanoma and carcinomas of stomach, rectum, liver, bladder, and prostate. These GSK212 871700-17-3 results correspond well with our present findings, which provided additional evidence for the…[Read more]

  • Davis Blalock posted an update 1 week, 1 day ago

    The ultimate goal of defoliants is to facilitate mechanical harvest, reduce trash and protect fiber and seed quality from weathering and staining by allowing earlier harvest. Another benefit is the reduced moisture content in the raw fibers and seed which is essential for storage of seedcotton. Selection of appropriate abscission chemicals is one…[Read more]

  • Clinically relevant models of heart injuries in mammals involve tissue death, typically due to ischemia. It is conceivable that necrotic tissue represents an obstacle to regeneration that also the zebrafish cannot overcome. To address this, we have established a cryoinjury model of the adult zebrafish heart. We find that zebrafish robustly…[Read more]

  • Besides breast cancer, aberrant expression of SATB1 was also correlated with advanced clinicopathologic factors and poor prognosis in cases of glioma, melanoma and carcinomas of stomach, rectum, liver, bladder, and prostate. These results correspond well with our present findings, which provided additional evidence for the concept that SATB1 plays…[Read more]

  • The clear cell renal cell carcinoma is the most common histopathological subtype, comprising 70-80% of all RCCs. Although considerable improvements have been made in diagnosis, surgical techniques and adjuvant therapies in last decades, patients with ccRCC still face a dismal clinical outcome owing to high rate of metastasis both at initial…[Read more]

  • Clinically relevant models of heart injuries in mammals involve tissue death, typically due to ischemia. It is conceivable that necrotic tissue represents an obstacle to regeneration that also the zebrafish cannot overcome. To address this, we have established a cryoinjury model of the adult zebrafish heart. We find that zebrafish robustly…[Read more]

  • Besides breast cancer, aberrant expression of SATB1 was also correlated with advanced clinicopathologic factors and poor prognosis in cases of glioma, melanoma and carcinomas of stomach, rectum, liver, bladder, and prostate. These results correspond well with our present findings, which provided additional evidence for the concept that SATB1 plays…[Read more]

  • The clear cell renal cell carcinoma is the most common histopathological subtype, comprising 70-80% of all RCCs. Although considerable improvements have been made in diagnosis, surgical techniques and adjuvant therapies in last decades, patients with ccRCC still face a dismal clinical outcome owing to high rate of metastasis both at initial…[Read more]

  • Davis Blalock posted an update 2 weeks ago

    Clinically relevant models of heart injuries in mammals involve tissue death, typically due to ischemia. It is conceivable that necrotic tissue represents an obstacle to regeneration that also the zebrafish cannot overcome. To address this, we have established a cryoinjury model of the adult zebrafish heart. We find that zebrafish robustly…[Read more]

  • Davis Blalock posted an update 2 weeks ago

    The clear cell renal cell carcinoma is the most common histopathological subtype, comprising 70-80% of all RCCs. Although considerable improvements have been made in diagnosis, surgical techniques and adjuvant therapies in last decades, patients with ccRCC still face a dismal clinical outcome owing to high rate of metastasis both at initial…[Read more]

  • Besides breast cancer, aberrant expression of SATB1 was also correlated with advanced clinicopathologic factors and poor prognosis in cases of glioma, melanoma and carcinomas of stomach, rectum, liver, bladder, and prostate. These results correspond well with our present findings, which provided additional evidence for the concept that SATB1 plays…[Read more]

  • Besides breast cancer, aberrant expression of SATB1 was also correlated with advanced clinicopathologic CT99021 factors and poor prognosis in cases of glioma, melanoma and carcinomas of stomach, rectum, liver, bladder, and prostate. These results correspond well with our present findings, which provided additional evidence for the concept that…[Read more]

  • The clear cell renal cell carcinoma is the most common histopathological subtype, comprising 70-80% of all RCCs. Although considerable improvements have been made in diagnosis, surgical techniques and adjuvant therapies in last decades, patients with ccRCC still face a dismal clinical outcome owing to high rate of metastasis both at initial…[Read more]

  • The clear cell renal cell carcinoma is the most common histopathological subtype, comprising 70-80% of all RCCs. Although considerable improvements have been made in diagnosis, surgical techniques and adjuvant therapies in last decades, patients with ccRCC still face a dismal clinical outcome owing to high rate of metastasis both at initial…[Read more]

  • Clinically relevant models of heart injuries in mammals involve tissue death, typically due to ischemia. It is conceivable that necrotic tissue represents an obstacle to regeneration that also the zebrafish cannot overcome. To address this, we have established a cryoinjury model of the adult zebrafish heart. We find that zebrafish robustly…[Read more]

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