Dan Jones

  • This positive staining pattern extends deep into the detrusor in an organized filamentous pattern which clearly delineates and surrounds smooth muscle bundles. These cells exhibit narrow elongated and branched cell processes. We therefore explored the possibility that NTPD2 positive cells were fibroblasts, myofibroblasts or neuronal in origin by…[Read more]

  • Dan Jones posted an update 1 day, 3 hours ago

    This positive staining pattern extends deep into the detrusor in an organized filamentous pattern which clearly delineates and surrounds smooth muscle bundles. These cells exhibit narrow elongated and branched cell processes. We therefore explored the possibility that NTPD2 positive cells were fibroblasts, myofibroblasts or neuronal in origin by…[Read more]

  • Dan Jones posted an update 1 day, 8 hours ago

    The absorption spectra of the nanoconjugates were recorded 15 minutes after incubation with 140 mM of sodium chloride. As expected, the naked GNPs showed a drastic red shift in the SPR band from 510 nm to around 600 nm confirming aggregation of uncovered nanoparticles. Salt induced aggregation was directly related to the increased loading of C225…[Read more]

  • Dan Jones posted an update 2 days, 3 hours ago

    The absorption spectra of the nanoconjugates were recorded 15 minutes after incubation with 140 mM of sodium chloride. As expected, the naked GNPs showed a drastic red shift in the SPR band from 510 nm to around 600 nm confirming aggregation of uncovered nanoparticles. Salt induced aggregation was directly related to the increased loading of C225…[Read more]

  • Dan Jones posted an update 2 days, 3 hours ago

    This positive staining pattern extends deep into the detrusor in an organized filamentous pattern which clearly delineates and surrounds smooth MK-2206 2HCl muscle bundles. These cells exhibit narrow elongated and branched cell processes. We therefore explored the possibility that NTPD2 positive cells were fibroblasts, myofibroblasts or neuronal…[Read more]

  • Dan Jones posted an update 2 days, 3 hours ago

    Despite vast efforts to detect and treat pancreatic cancer, the incidence and mortality rates remain virtually the same. Early diagnosis and efficient delivery of therapeutic agents to malignant cells remain the two major challenges in cancer management strategies. Monoclonal antibodies against growth factor receptors have been shown to be viable…[Read more]

  • Dan Jones posted an update 2 days, 7 hours ago

    This positive staining pattern extends deep into the detrusor in an organized filamentous pattern which clearly delineates and surrounds smooth muscle bundles. These cells exhibit narrow elongated and branched cell processes. We therefore explored the possibility that NTPD2 positive cells were fibroblasts, myofibroblasts or neuronal in origin by…[Read more]

  • Dan Jones posted an update 1 week ago

    Ong et al speculated the involvement of flow-sensing cilia, as mediator of ‘‘glomerulo-tubular balance’’ in the context of kidney. Glomerulo-tubular balance refers to the phenomenon which ensures that the rate of fluid re-absorption in the proximal renal tubule is always in proportion to the rate of glomerular filtration. This requires the presenc…[Read more]

  • Dan Jones posted an update 1 week ago

    Intriguingly, agroinfiltration in at least three independent experiments revealed that expression of mutant alleles M1, M3 to M8, and M20 to M23 together with Ave1 showed significantly compromised HR at five days post infiltration. In contrast, coexpression of Ave1 with the mutant alleles M2, M9-M19, and M24-M31 resulted in full HR. To exclude the…[Read more]

  • Dan Jones posted an update 1 week, 1 day ago

    Ong et al speculated the involvement of flow-sensing cilia, as mediator of ‘‘glomerulo-tubular balance’’ in the context of kidney. Glomerulo-tubular balance refers to the phenomenon which ensures that the rate of fluid re-absorption in the proximal renal tubule is always in proportion to the rate of glomerular filtration. This requires the presenc…[Read more]

  • Dan Jones posted an update 1 week, 1 day ago

    Ong et al speculated the involvement of flow-sensing cilia, as mediator of ‘‘glomerulo-tubular balance’’ in the context of kidney. Glomerulo-tubular balance refers to the phenomenon which ensures that the rate of fluid re-absorption in the proximal renal tubule is always in proportion to the rate of glomerular filtration. This requires the presenc…[Read more]

  • Dan Jones posted an update 1 week, 1 day ago

    Overall, our work shows that zebrafish cannot only restore surgically removed heart tissue, but also regenerate necrotic lesions. Since the latter type of injury is closer to the cardiac tissue damage seen in human patients, our results underscore the relevance of research into the cellular and molecular mechanisms of natural heart regeneration in…[Read more]

  • Dan Jones posted an update 1 week, 3 days ago

    However, as these Trp or Cys residues are conserved in many other plant eLRR proteins as well, they likely contribute to the conformation and stability of the protein rather than to ligand specificity. In addition, another site-directed mutagenesis strategy focused on putative N-linked glycosylation sites, which frequently occur in the eLRR domain…[Read more]

  • Dan Jones posted an update 1 week, 3 days ago

    Ong et al speculated the involvement of flow-sensing cilia, as mediator of ‘‘glomerulo-tubular balance’’ in the context of kidney. Glomerulo-tubular balance refers to the phenomenon which ensures that the rate of fluid re-absorption in the proximal renal tubule is always in proportion to the rate of glomerular filtration. This requires the presenc…[Read more]

  • Dan Jones posted an update 1 week, 3 days ago

    Overall, our work shows that zebrafish cannot only restore surgically removed heart tissue, but also regenerate necrotic lesions. Since the latter type of injury is closer to the cardiac tissue damage seen in human patients, our results underscore the relevance of research into the cellular and molecular mechanisms of natural heart regeneration in…[Read more]

  • Dan Jones posted an update 1 week, 3 days ago

    Ong et al speculated the involvement of flow-sensing cilia, as mediator of ‘‘glomerulo-tubular balance’’ in the context of kidney. Glomerulo-tubular balance refers to the phenomenon which ensures that the rate of fluid re-absorption in the proximal renal tubule is always in proportion to the rate of glomerular filtration. This requires the presenc…[Read more]

  • Dan Jones posted an update 2 weeks ago

    Intriguingly, agroinfiltration in at least three independent experiments revealed that expression of mutant alleles M1, M3 to M8, and M20 to M23 together with Ave1 showed significantly compromised HR at five days post infiltration. In contrast, coexpression of Ave1 with the mutant alleles M2, M9-M19, and M24-M31 resulted in full HR. To exclude the…[Read more]

  • Dan Jones posted an update 2 weeks, 1 day ago

    Ong et al speculated the involvement of flow-sensing cilia, as mediator of ‘‘glomerulo-tubular balance’’ in the context of kidney. Glomerulo-tubular balance refers to the phenomenon which ensures that the rate of fluid re-absorption in the proximal renal tubule is always in proportion to the rate of glomerular filtration. This requires the presenc…[Read more]

  • Dan Jones posted an update 2 weeks, 1 day ago

    Overall, our work shows that zebrafish cannot only restore surgically removed heart tissue, but also regenerate necrotic lesions. Since the latter type of injury is closer to the cardiac tissue damage seen in human patients, our results underscore the relevance of research into the cellular and molecular mechanisms of natural heart regeneration in…[Read more]

  • Dan Jones posted an update 2 weeks, 2 days ago

    However, as these Trp or Cys residues are conserved in many other plant eLRR proteins as well, they likely contribute to the WY 14643 conformation and stability of the protein rather than to ligand specificity. In addition, another site-directed mutagenesis strategy focused on putative N-linked glycosylation sites, which frequently occur in the…[Read more]

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